Anion Gap Calculator
Anion Gap
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Albumin-Corrected
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Interpretation
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Understanding the Anion Gap
AG = Na - (Cl + HCO3). Normal 3-12 mEq/L. Elevated indicates unmeasured anions, often from metabolic acidosis.
Albumin-corrected: for every 1 g/dL decrease in albumin below 4.0, AG decreases by ~2.5 mEq/L.
MUDPILES mnemonic identifies elevated AG causes: Methanol, Uremia, DKA, Propylene glycol, Isoniazid, Lactic acidosis, Ethylene glycol, Salicylates.
Disclaimer: This calculator is for informational purposes only and does not constitute financial, tax, or legal advice. Always consult a qualified professional for decisions specific to your situation.
Frequently Asked Questions
AG formula?
AG = Na - (Cl + HCO3). Some include K: AG = (Na+K) - (Cl+HCO3), normal 10-20.
Elevated AG causes?
MUDPILES: Methanol, Uremia, DKA, Propylene glycol, INH/Iron, Lactic acidosis, Ethylene glycol, Salicylates.
Normal range?
3-12 mEq/L (without K). AG >20 is significantly elevated, needs urgent evaluation.
Why correct for albumin?
Albumin is a major unmeasured anion. Low albumin reduces AG by ~2.5 per 1 g/dL decrease.